{"id":66,"date":"2005-09-16T16:25:30","date_gmt":"2005-09-16T20:25:30","guid":{"rendered":"http:\/\/blogs.law.harvard.edu\/rihlib\/2005\/09\/16\/on-false-research-findings\/"},"modified":"2012-05-07T15:33:28","modified_gmt":"2012-05-07T19:33:28","slug":"on-false-research-findings","status":"publish","type":"post","link":"https:\/\/archive.blogs.harvard.edu\/rihlib\/2005\/09\/16\/on-false-research-findings\/","title":{"rendered":"On false research findings"},"content":{"rendered":"<p><a name='a385'><\/a><\/p>\n<p>From PLoS Medicine: &#x201C;There is increasing concern that most current<br \/>\npublished research findings are false. The probability that a research<br \/>\nclaim is true may depend on study power and bias, the number of other<br \/>\nstudies on the same question, and, importantly, the ratio of true to no<br \/>\nrelationships among the relationships probed in each scientific field.<br \/>\nIn this framework, a research finding is less likely to be true when<br \/>\nthe studies conducted in a field are smaller; when effect sizes are<br \/>\nsmaller; when there is a greater number and lesser preselection of<br \/>\ntested relationships; where there is greater flexibility in designs,<br \/>\ndefinitions, outcomes, and analytical modes; when there is greater<br \/>\nfinancial and other interest and prejudice; and when more teams are<br \/>\ninvolved in a scientific field in chase of statistical significance.<br \/>\nSimulations show that for most study designs and settings, it is more<br \/>\nlikely for a research claim to be false than true. Moreover, for many<br \/>\ncurrent scientific fields, claimed research findings may often be<br \/>\nsimply accurate measures of the prevailing bias.&#x201D; (Sources: Daypop,<br \/>\nResourceShelf)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>From PLoS Medicine: &#x201C;There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific [&hellip;]<\/p>\n","protected":false},"author":1077,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1379],"tags":[],"class_list":["post-66","post","type-post","status-publish","format-standard","hentry","category-science-news"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/posts\/66","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/users\/1077"}],"replies":[{"embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/comments?post=66"}],"version-history":[{"count":1,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/posts\/66\/revisions"}],"predecessor-version":[{"id":542,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/posts\/66\/revisions\/542"}],"wp:attachment":[{"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/media?parent=66"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/categories?post=66"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/rihlib\/wp-json\/wp\/v2\/tags?post=66"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}