{"id":225,"date":"2006-11-26T22:44:57","date_gmt":"2006-11-27T03:44:57","guid":{"rendered":"http:\/\/blogs.law.harvard.edu\/neurovista\/2006\/11\/26\/rosai-dorfman-disease\/"},"modified":"2006-11-26T23:18:01","modified_gmt":"2006-11-27T04:18:01","slug":"rosai-dorfman-disease","status":"publish","type":"post","link":"https:\/\/archive.blogs.harvard.edu\/neurovista\/2006\/11\/26\/rosai-dorfman-disease\/","title":{"rendered":"Rosai-Dorfman Disease"},"content":{"rendered":"<p><a href=\"http:\/\/www.neurology.org\/cgi\/content\/short\/67\/9\/1551?rss=1\">Rosai-Dorfman disease presenting with widespread intracranial and spinal cord involvement<\/a>.<br \/>\nRosai-Dorfman disease is associated with a histiocytic infiltration of lymphoid tissue, but may also involve the orbit, nasopharynx, respiratory pathways, gastrointestinal tract, endocrine glands (particularly the thyroid), bone, and skin. Neurologic manifestations are rare, occurring in 4% of one series, and the diagnosis is often not made until pathology is available. <img decoding=\"async\" src=\"http:\/\/hosting.opml.org\/neurovista\/blog\/images\/rosaidorfman.gif\" alt=\"MRI scan\" align=\"right\">   Using data from two cases, we present the clinical manifestations, pathology, and treatment, and review the literature regarding the ocular and neurologic manifestations. Finally, we discuss the optimum management of this disorder.   [<a href=\"http:\/\/www.neurology.org\">Neurology current issue<\/a>] This Review highlights Rosai-Dorfman with CNS presentation.  <\/p>\n<hr>\n<p>Video Section<\/p>\n<p><a href=\"http:\/\/neurophilosophy.wordpress.com\/2006\/11\/22\/time-lapse-movies-of-oligodendrocyte-progenitor-migration\/\">Time-lapse movies of oligodendrocyte progenitor migration<\/a>. Oligodendrocytes are glial cells which form the myelin sheaths around axons in the central nervous system. These cells have a small number of cytoplasmic processes &#8211; the name oligodendrocyte comes from the Greek roots oligo, meaning few;, dendro meaning branch;, and kytos which denotes cell; &#8211; each of which forms a broad, flat structure after [&#8230;] [<a href=\"http:\/\/neurophilosophy.wordpress.com\">The Neurophilosopher&#8217;s weblog<\/a>]<\/p>\n<p><a href=\"http:\/\/neurophilosophy.wordpress.com\/2006\/11\/26\/webcastsplit-brain-surgery\/\">Webcast: Hemispherectomy surgery<\/a>. This film shows surgeons from the Neuroscience Institute at Le Bonheur Children&#8217;s Medical  Center perform a hemispher-ectomy on a 6-year-old girl with epilepsy. This involves removing a large part of the childs left hemisphere, and severing the corpus callosum, the bundle of approximately 100 million nerve fibres connecting the two hemispheres.<br \/>\nOne of [&#8230;] [<a href=\"http:\/\/neurophilosophy.wordpress.com\">The Neurophilosopher&#8217;s weblog<\/a>]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rosai-Dorfman disease presenting with widespread intracranial and spinal cord involvement. Rosai-Dorfman disease is associated with a histiocytic infiltration of lymphoid tissue, but may also involve the orbit, nasopharynx, respiratory pathways, gastrointestinal tract, endocrine glands (particularly the thyroid), bone, and skin. Neurologic manifestations are rare, occurring in 4% of one series, and the diagnosis is often [&hellip;]<\/p>\n","protected":false},"author":717,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-225","post","type-post","status-publish","format-standard","hentry"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/posts\/225","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/users\/717"}],"replies":[{"embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/comments?post=225"}],"version-history":[{"count":0,"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/posts\/225\/revisions"}],"wp:attachment":[{"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/media?parent=225"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/categories?post=225"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/archive.blogs.harvard.edu\/neurovista\/wp-json\/wp\/v2\/tags?post=225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}